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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK14
All Species:
26.97
Human Site:
S459
Identified Species:
45.64
UniProt:
O94921
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94921
NP_036527.1
469
53057
S459
R
A
F
G
K
N
N
S
Y
G
K
S
L
S
N
Chimpanzee
Pan troglodytes
XP_519189
469
53035
S459
R
A
F
G
K
N
N
S
Y
D
K
S
L
S
N
Rhesus Macaque
Macaca mulatta
XP_001102520
469
53072
S459
R
A
F
G
K
N
N
S
Y
G
K
S
L
S
N
Dog
Lupus familis
XP_532455
469
53036
S459
R
A
F
G
K
N
N
S
Y
G
K
S
L
S
N
Cat
Felis silvestris
Mouse
Mus musculus
O35495
469
52977
S459
R
A
F
G
K
N
N
S
Y
G
K
S
L
S
N
Rat
Rattus norvegicus
O35831
523
59414
V513
S
S
Y
P
E
T
G
V
F
V
I
N
H
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516045
337
37621
V328
A
F
P
G
M
K
D
V
Q
D
Q
L
E
R
I
Chicken
Gallus gallus
XP_418647
773
84016
S763
R
V
F
G
K
N
N
S
Y
G
K
G
V
S
N
Frog
Xenopus laevis
Q6DJM7
435
49211
S425
R
V
F
G
K
N
N
S
F
S
K
S
L
S
N
Zebra Danio
Brachydanio rerio
Q1RLU9
418
47889
T409
S
P
S
R
R
T
K
T
P
L
A
P
L
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523904
522
59750
I505
E
L
P
D
E
T
S
I
F
T
V
E
G
V
Q
Honey Bee
Apis mellifera
XP_624994
494
56118
N479
E
G
C
H
L
Y
T
N
S
R
H
G
C
A
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
E285
A
R
A
A
L
E
H
E
Y
F
K
D
L
G
G
Baker's Yeast
Sacchar. cerevisiae
P17157
305
34888
W296
K
Q
A
L
H
H
P
W
F
A
E
Y
Y
H
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.7
99.1
N.A.
98.5
43
N.A.
60.7
58.5
85.2
51.5
N.A.
48.4
50
N.A.
N.A.
Protein Similarity:
100
99.5
99.7
100
N.A.
99.3
59
N.A.
63.3
59.5
89.3
63.1
N.A.
61.2
63.3
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
100
0
N.A.
6.6
80
80
6.6
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
33.3
N.A.
20
86.6
86.6
26.6
N.A.
20
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
28.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.8
43.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
36
15
8
0
0
0
0
0
8
8
0
0
15
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
15
0
8
0
0
8
% D
% Glu:
15
0
0
0
15
8
0
8
0
0
8
8
8
0
0
% E
% Phe:
0
8
50
0
0
0
0
0
29
8
0
0
0
8
0
% F
% Gly:
0
8
0
58
0
0
8
0
0
36
0
15
8
8
8
% G
% His:
0
0
0
8
8
8
8
0
0
0
8
0
8
8
8
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% I
% Lys:
8
0
0
0
50
8
8
0
0
0
58
0
0
0
8
% K
% Leu:
0
8
0
8
15
0
0
0
0
8
0
8
58
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
50
50
8
0
0
0
8
0
0
50
% N
% Pro:
0
8
15
8
0
0
8
0
8
0
0
8
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
8
0
8
0
0
0
8
% Q
% Arg:
50
8
0
8
8
0
0
0
0
8
0
0
0
8
0
% R
% Ser:
15
8
8
0
0
0
8
50
8
8
0
43
0
50
0
% S
% Thr:
0
0
0
0
0
22
8
8
0
8
0
0
0
0
8
% T
% Val:
0
15
0
0
0
0
0
15
0
8
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
0
50
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _